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Mandatory Training

CITI Training must be completed prior to IACUC submission. Failure to do so will delay the IACUC review.

Click here for the list of mandatory animal training requirements.

What

Approval from the Institutional Animal Care and Use Committe (IACUC) is required for any activity involving vertebrate animals in biomedical research, training, or teaching. Applicants must submit an IACUC application describing:

  • Value of the animal research to human or animal health
  • Design of the study
  • Rationale and justification for using animals
  • Choice of species and rationale for sex of species used
  • Alternatives to the use of animals
  • Animal care procedures
  • How the welfare and well-being of the animals is going to be ensured during the course of the study

Who

Principal Investigators (PIs) who intend to conduct research utilizing vertebrate animals must complete an Institutional Animal Care and Use (IACUC) protocol and receive written approval from the IACUC. For information on who is eligible to be a PI, refer to Am I Eligible to be a PI?

When

Guidelines for when to submit by project type.

How

Vertebrate animal applications are submitted using the eIACUC system. For detailed information, refer to the IACUC website and eIACU Reference Guide.

Radiation Safety Office (RSO): Use of radioactive materials in animals requires specific authorization by the RSO. The review of animal protocols is coordinated through the Institutional IACUC. Refer to the Radiation Safety Guidelines.

IACUC Annual Renewal/Progress Report

An annual progress report is required to be provided to the IACUC via eIACUC.

  1. An Annual renewal (Progress Report) is required in year 1 and year 2 of the approved protocol.
  2. A Triennial renewal is required in year 3 of the protocol approval period. (Note- Year 3 annual renewal is imbedded in the triennial renewal smartform)

 

IACUC Protocol Closeout

What

Once a study has concluded and there is no plan to renew or continue the research outlined in an approved IACUC protocol, the Principal Investigator must ensure that the protocol has been closed and the IACUC has been informed regarding the disposition of the protocol.

When

A final report must be submitted within 1-10 business days of ending the study.

How

For detailed guidance on the final report and other requirements for close out, refer to Closing an IACUC Protocol.

IACUC Review Turnaround Time

Protocols involving minimal pain and distress to laboratory animals - turnaround time of ~ 10 days

Protocols involving risks of pain and distress to laboratory animals - turnaround time of ~ 3-4 weeks

Review turnaround time may be impacted by many variables including but not limited to quality and timelines of PI response to IACUC queries or required review by the IACUC Full board.

Learn More

Research 411 Portal

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