BioMe® BioBank Program
What
The BioMe® BioBank Program is an electronic medical record-linked biobank that enables researchers to conduct genetic, epidemiologic, molecular, and genomic studies on large collections of research specimens linked with medical information.
BioMe offers the following:
- DNA aliquots that may be used for interrogating genetic variation (genotyping) and/or chromosomal abnormalities
- Plasma
- Phenotypic data – BioMe Informatics and Genomic Analysis Center (BIGDASC)
- Genotypic data
- Whole exome sequence and genome-wide array data, through an agreement with the Regeneron Genetics Center
- Re-contacting services (recruitment method for separate prospective research requiring cohort of interest)
- DNA extraction services for non-clinical research samples
How
For more information or to request services, visit the BioMe BioBank.
The Institute for Personalized Medicine administration and faculty will review all research requests for scientific merit, clinical relevance, feasibility, and conformity with BioMe Biobank Program policies and guidelines.
Questions
Contact BioMe® BioBank
Biorepository and Pathology coRE
What
The Biorepository and Pathology coRE supports:
- Tissue and body fluid procurement
- Storage and tracking from consented and de-identified collections
- DNA, RNA and miRNA extraction
- Histology, special stains and tissue microarray generation
- Whole slide scanning and image analysis
- Immunohistochemical and immunofluorescent staining
- Laser capture microdissection
- Protocol development
How
Collection Activities
Researchers interested in collection activities should schedule a consultation with the Biorepository and Pathology CoRE Director.
Requests should include a detailed outline of the following:
- Specific aims of the research projects
- Specific tissue/body fluid requirements
- Scientific rationale
- Anticipated downstream techniques/assays of biospecimens
- Number of specimens requested
- Type of specimen preparation (fresh, frozen, RNA later, formalin fixed)
- Anticipated clinical information
Biospecimen Procurement
Please contact the Biorepository and Pathology CoRE Director for biospecimen distribution inquiries.
Questions
Rachel Brody MD, PhD
Director, Institutional Biorepository and Pathology CoRE
rachel.brody@mountsinai.org
Biorepository of WTC Solid Cancers
What
The Biorepository of World Trade Center (WTC) Solid Cancers is a resource that enables researchers to conduct studies on cancer etiology, biology, and outcome, as well as gene-environment interactions. The Biorepository of WTC Solid Cancer offers:
- cancer specific animal and human tissue samples
- comprehensive clinical and pathology information
- the responder samples are de-identified
LabVantage Biorepository Management System
What
ConduITS has implemented the LabVantage Biorepository Management System for the MSHS research community to reduce the barriers to entry for biospecimen collection. ConduITS provides the software licenses and maintains the servers, databases, and the application. ConduITS also provides consultation and basic training on project setup, master data entry, and label generation.
This biorepository management system can be used to support ad hoc sample collection as well as defined protocol-driven sample collection. Donor registration, consent, and common sample annotation can be captured in a single system to ease the future sample search and report. This system also uses role-based access control to protect donor’s privacy. This system tracks the sample processing, storage condition, and the chain of custody to provide a complete picture about a sample’s lineage.
How
To learn more contact:
Xin Zheng, PhD
xin.zheng@mssm.edu
Mount Sinai Imaging Research Warehouse (MS-IRW)
What
The Mount Sinai Imaging Research Warehouse (MS-IRW), developed by the BioMedical Engineering and Imaging Institute (BMEII) provides de-identified imaging data along with corresponding health records for over 1 million Mount Sinai patients. The images form the IRW can be linked to de-identified data from the MSDW or visa versa.
How
For more information contact:
Dr. Fayad
Dr. David Mendelson
david.mendelson@mountsinai.org
Neuropathology Brain Bank
What
The Neuropathology Brain Bank CoRE provides a flexible tissue repository platform to facilitate collection, characterization, and distribution of tissues and data for clinical and translational research projects with a neuropathology component.
The Neuropathology Brain Bank provides:
- Images (gross, photomicographs, and scanned slides)
- Brain tissue (fresh frozen, fixed, and FFPE)
- Neuropathology data and reports
- Assistance with experimental design
- Consultation services and training
Complete list of brain bank collections – Brain Collections at Mount Sinai
How
Tissues are made available to qualified investigators following internal review.
To access the neuropathology brain bank collection or to discuss other neuropathology services contact:
John F. Crary, MD-PhD
john.crary@mountsinai.org
Human Immune Monitoring Center (HIMC)
What
The Human Immune Monitoring Center (HIMC) in the Precision Immunology Institute offers biospecimen services including:
- Study design consultations for biospecimen protocols
- Blood and biospecimen processing
- Cell sorting and enrichment
- Biospecimen sample management
How
For more information, refer to the HIMC Biospecimen and Sample Management toggle.
PPHS Guidance - Future Use Data Sharing and Genetic Research
Research 411 Portal
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