Dr. Anuradha Lala-Trinadade, MD, and her team are developing SheAligned, a non-invasive, multimodal wearable platform designed for perimenopausal women. It integrates biosensing (e.g., skin temperature, heart rate variability, respiration, sleep, and sweat-based biomarkers including cortisol and sex hormones) with a mobile application that generates longitudinal cardiometabolic, sleep, and hormonal stability scores. In addition, women will participate in audiovisual-guided mind-body interventions that are triggered by physiologic stress markers. Together, these components form a system that predicts cardiometabolic risk and provides women with detailed information about their body to improve the management of perimenopausal symptoms.
Dr. Lala-Trinadade’s project will advance SheAligned from a defined concept toward an integrated, prototype-ready system for perimenopausal women. The work will focus on de-risking the core technical and user-experience elements of the platform: multimodal physiologic sensing, sweat-based biomarker measurement, mobile data visualization, and physiologically triggered audiovisual mind-body interventions. Her project will also refine clinical use cases and establish the evidence, development milestones, and partnerships required for a future pilot study and follow-on funding.
ConduITS is supported by NCATS of the NIH’s CTSA Program. Any use of CTSA-supported resources requires citation of grant number UL1TR004419 awarded to ISMMS in the acknowledgment section of every publication resulting from this support. Adherence to the NIH Public Access Policy is also required.
