Atomic Force Microscopy Core Facility

Clinical Research Unit (CRU)

CRU Website

What

The Clinical Research Unit (CRU) provides infrastructure to perform clinical and translational research studies including:

  • Outpatient Space
  • Nursing Support
  • Specimen Processing
  • Walk-in Phlebotomy
  • Pre-procedure COVID testing (for research studies only)

For more information refer to CRU Resources and watch the CRU Video Tour.

Equipment List and Photos

For a list of CRU equipment and photos, see the CRC Vault.

Fees

Refer to the CRU Fee Schedule.

Hours

8:00 AM – 5:30 PM (Monday – Friday, except hospital holidays)

Walk In Phlebotomy Services – 9:00 AM – 4:30 PM (Monday-Friday, except hospital )

How

Investigators interested in using CRU services must complete an application and receive approval from the CRU Administration Committee. Requests to use the CRU services may be assigned through the IRB/RUTH submission process by completing the Ancillary Review Form and assigning CRU via the Manage Ancillary Review tab.The CRU application can be completed by using the RUTH: Ancillary Office Survey form in Redcap. The redcap survey form must be uploaded and included with the IRB/RUTH submission. Applications should be completed in its entirety (budget page included). Investigators will receive notification of approval via email communication with the CRU and/or through RUTH.

When

Applications can be included with the IRB/RUTH submission. To avoid delays, investigators are encouraged to speak with the CRU, CRU@mssm.edu prior to submitting applications.

In-service

An in-service meeting with the CRU team may be required prior to scheduling services. At the in-service, the study protocol and procedures will be discussed to ensure that all of the elements are in place to safely and effectively begin the study. For more information refer to the web page – Clinical Research Unit (CRU).

Clinical Research

COVID Clinical Trials Unit (CTU)

The COVID Clinical Trials Unit (CTU), under the Division of Infectious Diseases, was established after the 1st wave of the pandemic to orchestrate the many ongoing COVID-19 clinical investigations throughout the Mount Sinai Health System (MSHS).

Since its inception, the COVID CTU has participated in several landmark COVID-19 studies, including the evaluations of the Regeneron monoclonal antibodies as well as the Pfizer and J&J vaccines. The COVID CTU continues to enroll research volunteers in both inpatient and outpatient settings.

To avoid overlapping efforts, all COVID-19-related clinical trials at MSHS, after receiving approval from the COVID-19 Protocol Review Committee, should then coordinate the study through the COVID CTU. All COVID-19 related protocols must be submitted to the COVID CTU for review and implementation. The COVID CTU will work directly with investigators to submit budgets, contracts, and other regulatory needs. Furthermore, the COVID CTU can provide research staffing support at most MSHS hospitals if additional staffing is needed.

For further information, please contact Debbie Lucy, COVID CTU Program Manager, at 212-824-7714 or email debbie.lucy@mssm.edu.

Department of Medicine Clinical Trials Office (CTO)

CTO Website

The Clinical Trials Office (CTO) provides infrastructure to support investigators within the Department of Medicine conduct industry sponsored clinical trials.

Resources

Genomics Core Facility (GCF)

Life Sciences Technology Laboratory

Molecular Modeling Core

Departmental Cores Website

The Molecular Modeling Core specializes in supporting research on macromolecular structures in silico studies of proteins and nucleic acids. Such studies can include:

Visualization

  • Ab initio structure prediction of small molecules (either using quantum mechanics or molecular mechanics)
  • Homology modeling of proteins
  • Virtual screening (docking)
  • Computer simulations (molecular dynamics or Monte Carlo)

The Core offers help in:

  • Installing and using visualization software (e.g., Pymol or VMD)
  • Structure prediction and manipulation software (e.g., Marvin, Avogadro)
  • Using software installed on our supercomputer, Minerva (e.g., Gaussian, Charmm, Amber, NAMD, and MMC; as well as several docking programs, such as Autodock-4, Autodock-Vina, eHiTS, PLANTS, and DOCK)

Students interested in molecular modeling tools can take the course “BSR2104 Intro to Computer Modeling & Macromolecules.” For assistance in using the Core, as well as tutorials and consultations, refer to the Mezei Laboratory site.

Mihaly Mezei, PhD, Director
Tel: (212) 659-5474 (x85475)
mihaly.mezei@mountsinai.org

Proteomics

Sinai BioDesign

Website

Sinai BioDesign is a technology and device incubator housed within the Department of Neurosurgery. The group is dedicated to a needs-driven approach to innovation in medicine, inspired and advised by Mount Sinai faculty and staff to translate clinical knowledge into commercially-relevant products. The group incorporates engineering, project management, and clinical resources towards its goal of empowering the Mount Sinai community to get innovations into the hands of physicians and patients alike. The group also supports research efforts in computational image processing and medical artificial intelligence with resources and mentorship through the AISINAI program.

Resources

  • Design & Engineering Consultations
  • Manual Fabrication
  • Digital Fabrication and Design
  • Medical Modeling
  • Prototyping
  • Equipment
    • 3D Printers
    • Laser Cutter
    • Parylene Deposition System
    • CNC mill
    • Hand and Power Tools
    • Other Postprocessing Capabilities

Artificial Intelligence Biodesign Fabrication Incubators Medical Devices

Scientific Computing

Scientific Computing Website

Scientific Computing provides the computational and data infrastructure to accelerate scientific discovery at Mount Sinai.

Resources

Scientific Computing & Data Science

Transfusion Medicine and Cellular Therapy Laboratories

Transfusion Medicine and Cellular Therapy Website

The Transfusion Medicine and Cellular Therapy Laboratories in the Department of Pathology, Molecular and Cell-Based Medicine provide infrastructure, expertise and services to support clinical research.

Resources

  • The Blood Bank
  • Cellular Therapy Laboratory
  • The Apheresis Center

Transfusion Medicine and Blood Bank

Tumor CytoGenomics Laboratory

Tumor CytoGenomics Website

The Tumor CytoGenomics Laboratory in the Department of Pathology, Molecular and Cell-Based Medicine, provides expertise in cancer cytogenetic techniques and analysis. The laboratory offers a full range of services to support clinical and basic research.

Resources

  • Tumor CytoGenomics Laboratory Clinical Services
  • Clinical Tests
  • Disease-Specific FISH Panels
  • Consultation Services

CytoGenomics