What does the Exposomics Core do?

Mar 24, 2026 | Conduits News, Edition 9

The Exposomics Core is at the cutting edge of research to quantify the exposome (i.e., nutrition, social risk factors, and chemical exposure) via lab assays, geospatial modeling, data mining and artificial intelligence. We disseminate our work to cultivate the public consciousness necessary to make meaningful changes in policies to build healthier communities through multi-investigator projects:

Center on Health and Environment Across the LifeSpan (HEALS)

The NIEHS-funded (P30ES023515) Center on Health and Environment Across the LifeSpan (HEALS) seeks to use a team-science, life-stage approach to identify how early life exposures contribute to disease and health inequities later in life; a transdisciplinary, big data science approach to understand how nutrition, the social environment, and other modifiers contribute to individual susceptibility; and translate research into novel, evidence-based approaches to disease prevention. Through the Center, they can provide researchers from a diverse array of disciplines access to the environmental health expertise and technology housed within the Institute through pilot grants, collaborations, and training.

Environmental influences on Child Health Outcomes (ECHO)

Environmental influences on Child Health Outcomes (ECHO) was designed to further understand the effects of environmental exposures on child health and development and builds off the existing Children’s environmental Health Exposure Analysis Resource (CHEAR) resource. Resources developed under CHEAR are an integral component of the ECHO program in providing state-of-the-art analytical support to measure environmental exposures for the extant cohorts solicited under ECHO.

Human Health Exposure Analysis Resource (HHEAR)

The goal of the NIH-funded Human Health Exposure Analysis Resource (HHEAR) Laboratory Network Hub is to provide the research community access to laboratory and statistical analyses to add or expand the inclusion of environmental exposures in their research and to make that data publicly available as a means to improve our knowledge of the comprehensive effects of environmental exposures on human health throughout the life course. Until HHEAR and its precursor, the Children’s Environmental Health Exposure Analysis Resource (CHEAR), it was not possible for researchers to keep pace with the rapid rate at which new chemicals are introduced. HHEAR represents a change in the philosophy of environmental research, moving towards acceptance of, and even embracing, data-driven science as a tool for chemical biomarker discovery. Data-driven research has led to an explosion of discoveries in genomics, epigenomics, proteomics, and metabolomics. Exposomics is a relatively new “omic” science that is rapidly evolving.

Children’s Environmental Health Center (CEHC)

The Children’s Environmental Health Center (CEHC) is the vehicle within the Institute for Exposomic Research that communicates groundbreaking research on exposomics and children’s environmental health to the general public, both locally and nationally. It connects our science to a growing national movement of supporters and communities committed to ensuring a healthier future for all.

 

ConduITS is supported by NCATS of the NIH’s CTSA Program. Any use of CTSA-supported resources requires citation of grant number UL1TR004419 awarded to ISMMS in the acknowledgment section of every publication resulting from this support. Adherence to the NIH Public Access Policy is also required.

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